Diagnosing and Managing Pustular Psoriasis: A Rare But Serious Disease

Pustular psoriasis is a group of rare psoriasis subtypes typified by aseptic, neutrophil-rich pustules. The three most common types are generalized pustular psoriasis, palmoplantar pustular psoriasis, and acrodermatitis continua of Hallopeau. The diagnosis of pustular psoriasis relies primarily on clinical features and may be difficult. Recent guidelines on diagnosis, classification, and assessment of severity have been published by ERASPEN and by the Japanese Dermatological Association.

Treatment of pustular psoriasis involves systemic therapy with cyclosporine, methotrexate or acitretin. Guidelines and a treatment algorithm have been published by the Japanese Dermatological Association. The understanding that IL-36 cytokines are likely the key driver of the autoimmune response in pustular psoriasis has led to the development of two novel, investigational monoclonal antibodies that target the IL-36 receptor. In addition, agents that target other molecules have also been investigated.

Diagnosing and Managing Pustular Psoriasis: A Rare But Serious Disease will provide clinicians with information about the most recent guidelines for diagnosing, classifying, and assessing the severity of pustular psoriasis. Current treatment guidelines and a review of agents in development will help clinicians manage this rare group of disorders.

Jointly provided by the Potomac Center for Medical Education and Rockpointe

In collaboration with the National Psoriasis Foundation

This activity is supported by an independent educational grant from Boehringer Ingelheim Pharmaceuticals, Inc.

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